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  • Assistant Professor, Patient Oriented Reseach, Feinstein Institutes for Medical Research
  • Director, Scleroderma and Raynaud Treatment Center and Epidemiology, Division of Rheumatology, Northwell Health

About the investigator

Dr. Sonali Narain is a board-certified rheumatologist with over 15 years of experience in rheumatology through her research and clinical experience. She currently serves as the Director of the Scleroderma and Raynaud Treatment Center and Epidemiology, Outcomes and Patient-Oriented Research in the Division of Rheumatology at Northwell Health.

Dr. Narain graduated from medical school in India and moved to the US for her Masters in Public Health-Epidemiology at the Univeristy of Florida, Gainesville, FL. It was here that her journey in rheumatology began. She initially worked in translational research in studying biomarkers in rheumatic diseases under the mentorship of Dr. Westley Reeves. She then moved to Massachussettes where she completed her Internal Medicine Residency training at Metrowest Medical Center, Framingham, MA. This was followed by a fellowship in rheumatology at Hospital for Special Surgery, New York NY. During her fellowship, under the mentorship of Dr. Jane Salmon, her research was focussed on characterizing the role of S1P dysregulation as a pathogenic factor in vascular injury in SLE. This proposal was awarded funding through the Empire Clinical Research Investigator Program (ECRIP) in 2014.

She has authored papers and textbook chapters and also presented at national meetings. She is an active member of the Americal College of Rheumatology (ACR).

Research focus

  • Systemic lupus erythematosus
  • Sjogren’s syndrome
  • Systemic sclerosis


University of Florida College of Public health and Health Professions
Degree: MPH

Sri Adichunchanagiri Institue of Medical Sciences
Degree: MBBS

Honors & awards

  • 2011 Best Teaching Resident


  1. Narain S, Furie R. “Update on clinical trials in systemic lupus erythematosus.” Curr Opin Rheumatol. 2016 Sep;28(5):477-87.
  2. DeFilippis EM, Narain S, Sobol I, Narula N, Bass A, Erkan D. “Rapidly Progressive Cardiac Failure Due to Giant Cell Myocarditis: A Clinical Pathology Conference Held by the Division of Rheumatology at Hospital for Special Surgery.” HSS J. 2015 Jul; 11(2):182-6
  3. Ramsden-Stein, D, Narain, S, Lockshin, MD. “Retiform purpura Initially Concerning for Granulomatosis with Polyangiitis” Grand Rounds from HSS, Management of Complex Cases, Fall 2012, Vol 3, Issue 3
  4. Kakumanu P, Sobel ES, Narain S, Li Y, Akaogi J, Yamasaki Y, Segal MS, et al. “Citrulline dependence of anti-cyclic citrullinated peptide antibodies in systemic lupus erythematosus as a marker of deforming/erosive arthritis.” J Rheumatol. 2009 Dec;36(12):2682-90
  5. Li Y, Lee PY, Sobel ES, Narain S, Satoh M, Segal MS, Reeves WH, Richards HB. “Increased expression of FcgammaRI/CD64 on circulating monocytes parallels ongoing inflammation and nephritis in lupus.” Arthritis Res Ther. 2009;11(1):R6.
  1. Lee PY, Li Y, Richards HB, Chan FS, Zhuang H, Narain S, Butfiloski EJ, Sobel ES, Reeves WH, Segal MS, “Type I Interferon: A Novel Risk Factor for EPC Depletion and Endothelial Dysfunction in SLE.” Arthritis Rheum. 2007 Nov;56(11):3759-69
  2. Kelly-Scumpia KM, Nacionales DC, Scumpia PO, Weinstein JS, Narain S, Moldawer LL, Satoh M, Reeves WH. “In vivo adjuvant activity of the RNA component of the Sm/RNP lupus auto antigen.” Arthritis Rheum. 2007 Sep 28;56(10):3379-3386
  3. Yamasaki Y, Narain S, Yoshida H, Hernandez L, Barker T, Hahn PC, Sobel ES, Segal MS, Richards HB, Chan EKL, Reeves WH, Satoh M. “Autoantibodies to RNA helicase A: A new serological marker of early lupus.” Arthritis Rheum. 2007 Feb; 56 (2):596-604.
  4. Yamasaki Y, Honkanen-Scott M, Hernandez L, Ikeda K, Barker T, Bubb MR, Narain S, Richards HB, Chan EK, Reeves WH, Satoh M. “Nucleolar staining cannot be used as a screening test for the scleroderma marker anti-RNA polymerase I/III antibodies.” Arthritis Rheum. 2006 Aug 31; 54(9):3051-3056
  5. Li Y, Tucci M, Narain S, Barnes EV, Sobel ES, Segal MS, Richards HB. “Urinary biomarkers in lupus nephritis.” Autoimmun Rev. 2006 Jul; 5(6):383-8.
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