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  • Professor, Center for Health Innovations and Outcomes Research (CHIOR), Feinstein Institutes for Medical Research
  • Assistant Vice President, Director and Professor, Biostatistics Unit, Feinstein Institutes for Medical Research
  • Professor, Molecular Medicine & Population Health, Donald and Barbara Zucker School of Medicine at Hofstra/Northwell

About the investigator

As a biostatistician, Dr. Lesser’s job is to help doctors and scientists (“investigators”) make sense out of the information obtained in a research study. This is done by using advanced mathematical and statistical methods to help answer research questions. His work involves more than just data analysis. He also helps investigators formulate their research questions, design the study, manage, store and retrieve the data, prepare publications, monitor patient safety and data quality. His training is in mathematics and mathematical statistics.

Dr. Lesser has been a member of numerous grant committees at the National Institute of Health (NIH). Most of this work has been for the National Cancer Institute, National Center for Complementary and Alternative Medicine, and the National Institute of Allergy.

Martin L Lesser, PhD, is also Chair of the Institutional Review Board. Dr. Lesser’s areas of statistical interest are design and analysis of clinical trials, clinical epidemiology, longitudinal data, non-parametric and robust methods, diagnostic testing and screening and classification problems. Much of his career has been devoted to oncology, HIV/AIDS, OB/Gyn, and cardiovascular disease.


Cornell University, Ithaca, NY
Degree: BA
Field of study: Mathematics

Rutgers University, New Brunswick, NJ
Degree: MS
Field of study: Statistics

Rutgers University, New Brunswick, NJ
Degree: PhD
Field of study: Statistics

Columbia University School of Public Health, New York, NY
Field of study: Epidemiology

CMDNJ, Rutgers Medical School, Piscataway, NJ
Field of study: Epidemiology


  • 1974-1978 Teaching Assistant and Instructor, Department of Statistics, Rutgers University
  • 1978-1982 Assistant Member, Biostatistics Laboratory, Memorial Sloan-Kettering Cancer Center (MSKCC), NY; Member, Clinical Investigations Committee (IRB), MSKCC; Assistant Professor, Biostatistics Unit, Cornell University Graduate School of Medical Sciences (CUGSMS), NY
  • 1978-1996 Assistant and Associate Professor of Biostatistics, Cornell University Graduate School of Medical Sciences, Albert Einstein College of Medicine and Cornell University Medical College.
  • 1982-1985 Director, Department of Biostatistics, Montefiore Medical Center (MMC), Bronx, NY; Assistant Professor, Department of Epidemiology and Social Medicine, Albert Einstein College of Medicine, Bronx, NY; Member, Research Committee (IRB), MMC, Bronx, NY; Member, Decision Support Systems Committee, MMC, Bronx, NY
  • 1985-present Chairman (1999-Present) & Member (1985-1999), Institutional Review Board (IRB Committee B), Northwell Health, Manhasset, NY
  • 1985-1990 Assistant Professor of Biostatistics, Department of Public Health, Weill Medical College of Cornell University, New York, NY
  • 1985-present Director and Investigator, Biostatistics Unit, Feinstein Institutes for Medical Research, Northwell Health, Manhasset, NY
  • 1989-2007 Associate Professor of Biostatistics, Department of Public Health, Weill Medical College of Cornell University, New York, NY
  • 1989-1998 Adjunct Professor, Department of Health Sciences, Long Island University, – CW Post Campus, NY
  • 1996-2002 Associate Professor, Department of Environmental Medicine, NYU School of Medicine, New York, NY
  • 1997-present Judge, Long Island Science and Engineering Fair
  • 1998-present Training Coordinator, East Rockaway Fire Department Rescue Squad, New York, NY
  • 2003-present Professor, Elmezzi Graduate School of Molecular Medicine, Feinstein Institutes for Medical Research, Northwell Health, Manhasset, NY
  • 2004-present Senior Faculty Advisor for Research Affairs, Department of Emergency Medicine, North Shore University Hospital, Manhasset, NY
  • 2008-present Clinical Professor of Biostatistics, Department of Public Health, Weill Medical College of Cornell University, NY
  • 2009-present Professor, Department of Molecular Medicine, Hofstra Northwell School of Medicine
  • 2011-present Professor, Department of Population Health, Hofstra Northwell School of Medicine
  • 2011 The Evolution of Biostatistics, Presentation to Hofstra University undergraduate math majors to acquaint them with the beauty of statistics and its basis to mathematics.
  • 2012 -present Adjunct Professor, School of Health Professions, Hofstra University, Hempstead, NY


  1. Tang CC, Poston KL, Eckert T, Feigin A, Frucht S, Gudesblatt M, Dhawan V, Lesser M, Vonsattel JP, Fahn S, Eidelberg D. “Differential Diagnosis of Parkinsonism: A Metabolic Imaging Study Using Pattern Analysis.” Lancet Neurology, 2010 Feb;9(2):149-58. Epub 2010 Jan 8.
  2. Manu P, Tsang J, Napolitano BA, Lesser ML, Correll CU. “Predictors of Insulin Resistance in Obese with Metabolic Syndrome.” European Journal of Internal Medicine, 2010 Oct; 21(5):409-13. Epub 2010
  3. Lustbader D, Pekmezaris R, Frankenthaler M, Walia R, Smith F, Hussain E, Napolitano B, Lesser M. “Palliative Medicine Consultation Impacts DNR Designation and Length of Stay for Terminal Medical MICU Patients.” Palliative & Supportive Care. 2011 Dec;9(4):401-6.
  4. Wang D, Pezo RC, Corner G, Sison C, Lesser ML, Shenoy SM, Mariadason JM, Singer RH, Augenlicht LH. “Altered Dynamics of Intestinal Cell Maturation in Apc1638N/+ Mice.” Cancer Research. 2010 Jul 1;70(13):5348-57.
  5. Silverman RA, Arora H, Kwiatkowski TM, Graff KK, Baneman E, Kohn N, Bowman CF, Smith KN, Lesser, ML. “Increased A1C Among Adult Emergency Department Patients With Type 2 Diabetes.” Annals of Emergency Medicine. Ann Emerg Med. 2011 Jun;57(6):575-81. Epub 2011 Jan 12.
  1. Wagner B, Meirowitz N, Shah J, Nanda D, Reggio L, Cohen P, Britt K, Kaufman L, Walia R, Bacote C, Lesser ML, Pekmazaris R, Fleischer A, Abrams KJ. “Comprehensive Perinatal Safety Initiative to Reduce Adverse Obstetric Events.” Wiley Online Library: 1 Mar 2011 DOI: 10.1111/j.1945-1474.2011.00134.
  2. Huang W, Moisini I, Bethunaickan R, Sahu R, Akerman M, Eilat D, Lesser M, Davidson A. “BAFF/APRIL Inhibition Decreases Selection of Naïve But Not Antigen Induced Autoreactive B Cells in Murine SLE.” Journal of Immunology. 2011 Dec 15;187(12):6571-80. Epub 2011 Nov 18.
  3. Sam S, Pekmezaris R, Nouryan CN, Tan R, Conrardy A, Ward MF, Schwalberg A, Vij B, Silverman H, Guzik H, Lesser ML,Wolf-Klein GP. “Survey of Emergency Medical Services Professionals’ Experience with Advance Directives and Medical Orders for Life-Sustaining Treatment (MOLST).” Journal of the American Geriatrics Society, 59(12):2383-2384, December 2011.
  4. Barnett BJ, Nunberg S, Tai J, Lesser ML, Fridman V, Nichols P, Powell R, Silverman R. “Oral and Tympanic Membrane Temperatures are Inaccurate to Identify Fever in Emergency Department Adults.” West Journal of Emergency Medicine. 2011 Nov;12(4):505-11.
  5. Budman DR, Calabro A, Rosen L, Lesser M. “Identification of Unique Synergistic Drug Combinations Associated with Down Expression of Surviving in a Preclinical Breast Cancer Model System.” Anti-Cancer Drugs. In Press 2011.
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