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  • Professor & Head, Feinstein Center for Neurosciences, Feinstein Institutes for Medical Research
  • Professor of Molecular Medicine and Neurology, Donald and Barbara Zucker School of Medicine at Hofstra/Northwell

About the investigator

David Eidelberg, MD, is the Susan and Leonard Feinstein Professor of Neurology and Neuroscience, and has served as director of the Center for Neurosciences at the Feinstein Institutes for Medical Research since its founding in 2001. A neurologist and neuroscientist, he is widely regarded for his pioneering work on network dysfunction in brain disease.

He was first to identify metabolic networks as systems-level disease biomarkers in patients and has described previously unrecognized network pathologies. His approach is currently being used worldwide for the assessment of disease progression and treatment responses, and as an adjunct to clinical diagnosis.

Dr. Eidelberg received his medical degree from Harvard Medical School. He completed his residency in neurology there, followed by postdoctoral training in brain imaging in London and New York. Dr. Eidelberg has authored over 250 peer-reviewed original articles, 100 reviews and editorials, and an edited volume (Imaging in Parkinson’s Disease, Oxford University Press, 2011). He serves on the editorial boards of several major journals, and is editor-in-chief (Western Hemisphere) of Current Opinion in Neurology. Dr. Eidelberg has received numerous grants and awards, including the 2018 Bachmann Strauss Prize for his pioneering research in dystonia. He is a member of the Association of American Physicians. 

Research focus

Dr. Eidelberg directs a leading imaging research program in brain disease. His program is internationally recognized for developing novel imaging techniques to characterize and quantify neural circuits in neurodegenerative disorders and to study their modulation by using functional imaging with PET and fMRI.

Lab members

Joseph Carrión, PhD
Research Scientist
Research: Dr. Carrión is a research scientist who operates the Lab for Behavioral and Molecular Neuroimaging (LBMN) as a core facility of the Feinstein Institutes for Medical Research. He assists research investigators with designing and implementing small animal protocols using Micro Positron Emission Tomography (MicroPET). Dr. Carrión oversees image acquisition, quality control, as well as data management and analysis for the MicroPET facility. He is a member of the Institutional Animal Care and Use Committee (IACUC) at Northwell.
Email: [email protected]

Vijay Dhawan, PhD
Professor
Research: Dr. Dhawan’s research focuses on the use of novel radiotracers in functional brain imaging and studies the alterations in brain dopaminergic system that occurs in Parkinson’s disease and other movement disorders.
Email: [email protected]

Yilong Ma, PhD
Associate Professor
Research: Dr. Ma works on the development and application of brain imaging methodology in the study of neurodegenerative and neuropsychiatric disorders.
Email: [email protected]

Paul Mattis, PhD
Assistant Investigator
Research: Dr. Mattis’ research focuses on the neuropsychology of movement disorders, with special interest in the relationship between cognitive functioning and metabolism brain networks.
Email: [email protected]

Martin Niethammer, MD, PhD
Assistant Professor
Research: Dr. Niethammer’s research focuses on the use of neuroimaging in the investigation of Parkinson’s disease and dystonia.
Email: [email protected]

Shichun Peng, PhD
Assistant Investigator
Research: Dr. Peng’s research interests are in medical image processing and analysis with a focus on pattern recognition and multi-modality correlation.
Email: [email protected]

Katharina Schindlbeck, MD
Research Scientist
Research: Dr. Schindlbeck is a research scientist who is studying disease-relevant pattern expressions in patients with specific genetic susceptibility factors.
Email: [email protected]

Phoebe Spetsieris, PhD
Professor
Research: Dr. Spetsieris uses an integrated methodologies approach to develop a versatile PC based package (SCANVP) that has been widely used in multi-modal functional image data visualization and analysis.
Email: [email protected]

Chris Chengke Tang, MD, PhD
Assistant Professor
Research: Dr. Tang's research focuses on studying metabolic brain networks related to motor and cognitive abnormalities in neurodegenerative diseases.
Email: [email protected]

An Vo, PhD
Assistant Professor
Research: Dr. Vo’s research interests are in functional magnetic resonance imaging (fMRI) processing and analysis of neurodegenerative disease.
Email: [email protected]

Administration

Yoon Young (Michelle) Choi, MS, CCRC
Research Coordinator
Email: [email protected]

Christine Edwards, MA
Administrative Director
Email: [email protected]

Toni Fitzpatrick, MS, CCRC
Sr. Research Coordinator
Email: [email protected]

Rosie Persaud
Administrative Manager
Email: [email protected]

Loreta Quartarolo, BS
Sr. Research Coordinator
Email: [email protected]

Education

Columbia University, New York, NY
Degree: BA
1977

Harvard Medical School, Boston, MA
Degree: MD
1981

Appointments

  • Susan and Leonard Feinstein Professor of Neurology and Neuroscience
  • Donald and Barbara Zucker School of Medicine at Hofstra/Northwell
  • Scientific Advisory Board, Michael J Fox Foundation for Parkinson’s Research
  • Scientific Advisory Board, Dystonia Medical Research Foundation
  • Scientific Advisory Board, Collaborative Center for X-Linked Dystonia-Parkinsonism
  • Study Section Member, National Institutes of Health, Clinical Trials Committee (ZRG1 BDCN-W (55) R)
  • Study Section Member, National Institutes of Health, Clinical Neuroscience and Neurodegeneration (CNN)
  • Member, Association of American Physicians (AAP)

Honors & awards

2019 Elected as a member to the Association of American Physicians
2018 The Bachmann-Strauss Prize for Excellence in Dystonia Research
2010 Movement Disorders Research Award, American Academy of Neurology
2005 Fred Springer Award, American Parkinson’s Disease Association

Publications

  1. Argyelan M, Carbon M, Niethammer M, Ulug AM, Henning UV, Bressman SB, Dhawan V, Eidelberg D (2009) “Cerebello-thalamo-cortical connectivity regulates penetrance in dystonia.” J Neurosci 29(31):9740-9747.
  2. Tang C, Poston K, Eckert T, Feigin A, Frucht S, Gudesblatt M, Dhawan V, Lesser M, Vonsattel J-P, Fahn S, Eidelberg D (2010) “Differential diagnosis of parkinsonism: a metabolic imaging study using pattern analysis.” Lancet Neurol 9(2):149-158.
  3. Tang C, Poston K, Dhawan V, Eidelberg D (2010) “Abnormalities in metabolic network activity precede the onset of motor symptoms in Parkinson’s disease.” J Neurosci 30(3):1049-1056.
  4. Mure H, Hirano S, Tang CC, Isaias IU, Antonini A, Ma Y, Dhawan V. Eidelberg D (2011)
    “Parkinson’s disease tremor-related metabolic network: characterization, progression, and treatment effects.” NeuroImage 54(2): 1244-1253.
  5. Tang C, Feigin A, Ma Y, Habeck C, Paulsen JS, Teune LK, Leenders KL, Guttman M, Dhawan V, Eidelberg D (2013) “Metabolic network activity as a progression biomarker of premanifest Huntington’s disease.” J Clin Invest 123 (9): 4076-4088.
  1. Ko JH, Feigin A, Mattis PJ, Tang CC, Ma Y, Dhawan V, During MJ, Kaplitt MG, Eidelberg D (2014) “Network modulation following sham surgery in Parkinson’s disease.” J Clin Invest 124(8): 3656-3666.
  2. Holtbernd F, Gagnon JF, Postuma RB, Ma Y, Tang CC, Feigin A, Dhawan V, Vendette M, Soucy JP, Eidelberg D , Montplaisir J [Co-corresponding authors] (2014) “Abnormal metabolic network activity in REM sleep behavior disorder.” Neurology 82(7): 620-627.
  3. Vo A, Sako W, Niethammer M, Carbon M, Bressman SB, Ulug AM, Eidelberg D (2015) “Thalamocortical connectivity correlates with phenotypic variability in dystonia.” Cereb Cortex 25(9): 3086-3094.
  4. Mattis PJ, Niethammer M, Sako W, Tang CC, Nazem A, Gordon ML, Brandt V, Dhawan V, Eidelberg D (2016) “Distinct brain networks underlie cognitive dysfunction in Parkinson’s and Alzheimer’s diseases.” Neurology 87(18):1925-1933.
  5. Niethammer M, Tang CC, Vo A, Nguyen N, Spetsieris P, Dhawan V, Ma Y, Small M, Feigin A, During MJ, Kaplitt MG, Eidelberg D (2018) “Gene therapy mitigates Parkinson’s disease symptoms by reorganizing functional brain connectivity. Sci Transl Med 10(469): eaau0713.
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